Vitamin C

 

What is Vitamin C?

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin essential for various bodily functions, including immune support, collagen synthesis, antioxidant protection, and neurotransmitter function. It cannot be produced by the body and must be obtained from dietary sources or supplements.

 

 

Connection Between Vitamin C and Autism

Oxidative Stress and Autism

• Children with autism spectrum disorder (ASD) often exhibit higher levels of oxidative stress, which can damage cells and disrupt brain function.

• Vitamin C, as a powerful antioxidant, helps reduce oxidative damage, supporting better cell function and reducing inflammation.
   

Neurotransmitter Function

• Vitamin C plays a critical role in the synthesis of neurotransmitters like dopamine and serotonin, which are often dysregulated in autism. Proper neurotransmitter function is essential for mood, behavior, and cognitive processes.
   

Behavioral and Sensory Improvements

• Studies have shown that Vitamin C supplementation may improve stereotypical behaviors (repetitive movements) in children with autism.

• It may also reduce hyperactivity, irritability, and improve social interaction when oxidative stress is mitigated.
  
   

 

Deficiency in Vitamin C

Signs of Deficiency

• Fatigue

• Irritability

• Increased susceptibility to infections

• Poor wound healing

• Dry skin and hair

• In severe cases, scurvy, characterized by bleeding gums and joint pain, though rare in developed countries.
   

Deficiency and Autism

• Children with autism may be at a higher risk of deficiency due to limited food preferences, sensory sensitivities, or restricted diets.
  
   

 

Sources of Vitamin C

1. Fruits

   • Oranges

   • Strawberries

   • Kiwifruit

   • Guava

   • Papaya
      

2. Vegetables

   • Bell peppers

   • Broccoli

   • Brussels sprouts

   • Kale

   • Tomatoes
     
      

 

Supplement Forms for Autism

• L-Ascorbic Acid: Most common and bioavailable form.

• Sodium Ascorbate: Less acidic, gentler on the stomach, suitable for sensitive children.

• Liposomal Vitamin C: Encapsulated form for improved absorption.
  
   

 

Dosage of Vitamin C for Children with Autism

Recommended Daily Allowance (RDA)

• 1-3 years: 15 mg/day

• 4-8 years: 25 mg/day

• 9-13 years: 45 mg/day

• 14-18 years: 65-75 mg/day
   

Therapeutic Dosage

• For oxidative stress or behavioral support in autism, doses ranging from 200-500 mg/day have been studied.

• High doses (up to 1,000 mg/day) may be used under medical supervision to address oxidative stress or specific symptoms, but exceeding this may lead to gastrointestinal discomfort.
   

 

Toxicity and Precautions

• Vitamin C is water-soluble, and excess amounts are excreted in urine, making toxicity rare.

• High doses can cause side effects like diarrhea, stomach cramps, and nausea.
   

 

Testing for Deficiency

• Blood tests can measure Vitamin C levels to confirm deficiency and guide appropriate supplementation.
  
   

 

Key Takeaway for Parents

Vitamin C supplementation may benefit children with autism by reducing oxidative stress, supporting neurotransmitter function, and improving behavior. Always consult a healthcare provider to determine the best dosage and form tailored to your child’s needs.